null
SMILES: [O-][N+](=O)c1ccc(CCNC(=O)C(Cl)Cl)cc1
InChI Key: InChIKey=DUDPYHGWFFLHRW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 1A1 (Rattus norvegicus) | BDBM50027799 (CHEMBL1908215 | N-(2-Pnitrophenethyl) Dichloro Ace...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Mechanism based inhibition of rat cytochrome P450 CYP1A1 measured by ethoxyresorufin O-deethylation warfarin R-6 and R-8 hydroxylation | Curr Drug Metab 6: 413-54 (2005) BindingDB Entry DOI: 10.7270/Q2VQ33X3 | |||||||||||
More data for this Ligand-Target Pair |