BDBM50027961 CHEMBL3360257::US10849901, Compound 126

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12

InChI Key: InChIKey=BKEZPAKTGANESH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ADP-ribosylation factor 6 (Human)	BDBM50027961 (CHEMBL3360257 | US10849901, Compound 126) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12 Show InChI InChI=1S/C20H21NO3S/c1-20(2,3)14-8-10-15(11-9-14)25(23,24)21-18-12-13-19(22)17-7-5-4-6-16(17)18/h4-13,21-22H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Navigen, Inc.; The University of Utah Research Foundation US Patent					Assay Description The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...				US Patent US10849901 (2020)
					More data for this Ligand-Target Pair
Cytochrome b-c1 complex subunit 7 (Homo sapiens (Human))	BDBM50027961 (CHEMBL3360257 | US10849901, Compound 126) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12 Show InChI InChI=1S/C20H21NO3S/c1-20(2,3)14-8-10-15(11-9-14)25(23,24)21-18-12-13-19(22)17-7-5-4-6-16(17)18/h4-13,21-22H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis				J Med Chem 57: 7990-8 (2014) Article DOI: 10.1021/jm500863j BindingDB Entry DOI: 10.7270/Q24Q7WK4
					More data for this Ligand-Target Pair