null
SMILES: COc1ccc2[nH]c3c(c(n[nH]c3=O)-c3ccco3)c2c1
InChI Key: InChIKey=MQTOHMJPTGWEHD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50028097 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50028097
(CHEMBL3338888)Show InChI InChI=1S/C15H11N3O3/c1-20-8-4-5-10-9(7-8)12-13(11-3-2-6-21-11)17-18-15(19)14(12)16-10/h2-7,16H,1H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of p110alpha (unknown origin) |
Bioorg Med Chem Lett 24: 5037-40 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.017 BindingDB Entry DOI: 10.7270/Q27H1M51 |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50028097
(CHEMBL3338888)Show InChI InChI=1S/C15H11N3O3/c1-20-8-4-5-10-9(7-8)12-13(11-3-2-6-21-11)17-18-15(19)14(12)16-10/h2-7,16H,1H3,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of DYRK1A (unknown origin) |
Bioorg Med Chem Lett 24: 5037-40 (2014)
Article DOI: 10.1016/j.bmcl.2014.09.017 BindingDB Entry DOI: 10.7270/Q27H1M51 |
More data for this Ligand-Target Pair | |