BDBM50028116 CHEMBL3353988

SMILES: COc1ccc(cc1)-c1ccc2N([C@@H](C)C[C@@H](Nc3ccccc3)c2c1)C(C)=O

InChI Key: InChIKey=KRQNRCGKZXQJBI-BXKMTCNYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50028116 (CHEMBL3353988) Show SMILES COc1ccc(cc1)-c1ccc2N([C@@H](C)C[C@@H](Nc3ccccc3)c2c1)C(C)=O |r| Show InChI InChI=1S/C25H26N2O2/c1-17-15-24(26-21-7-5-4-6-8-21)23-16-20(11-14-25(23)27(17)18(2)28)19-9-12-22(29-3)13-10-19/h4-14,16-17,24,26H,15H2,1-3H3/t17-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD2 (1 to 473 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50028116 (CHEMBL3353988) Show SMILES COc1ccc(cc1)-c1ccc2N([C@@H](C)C[C@@H](Nc3ccccc3)c2c1)C(C)=O |r| Show InChI InChI=1S/C25H26N2O2/c1-17-15-24(26-21-7-5-4-6-8-21)23-16-20(11-14-25(23)27(17)18(2)28)19-9-12-22(29-3)13-10-19/h4-14,16-17,24,26H,15H2,1-3H3/t17-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD4 (1 to 477 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50028116 (CHEMBL3353988) Show SMILES COc1ccc(cc1)-c1ccc2N([C@@H](C)C[C@@H](Nc3ccccc3)c2c1)C(C)=O |r| Show InChI InChI=1S/C25H26N2O2/c1-17-15-24(26-21-7-5-4-6-8-21)23-16-20(11-14-25(23)27(17)18(2)28)19-9-12-22(29-3)13-10-19/h4-14,16-17,24,26H,15H2,1-3H3/t17-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD3 (1 to 475 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair