BDBM50028172 CHEMBL3354010

SMILES: COc1ccc(cc1)-c1ccc2N(CC[C@@H](Nc3ccccc3)c2c1)C(C)=O

InChI Key: InChIKey=RQQNIOYWIPRSRO-HSZRJFAPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50028172 (CHEMBL3354010) Show SMILES COc1ccc(cc1)-c1ccc2N(CC[C@@H](Nc3ccccc3)c2c1)C(C)=O |r| Show InChI InChI=1S/C24H24N2O2/c1-17(27)26-15-14-23(25-20-6-4-3-5-7-20)22-16-19(10-13-24(22)26)18-8-11-21(28-2)12-9-18/h3-13,16,23,25H,14-15H2,1-2H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD2 (1 to 473 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50028172 (CHEMBL3354010) Show SMILES COc1ccc(cc1)-c1ccc2N(CC[C@@H](Nc3ccccc3)c2c1)C(C)=O |r| Show InChI InChI=1S/C24H24N2O2/c1-17(27)26-15-14-23(25-20-6-4-3-5-7-20)22-16-19(10-13-24(22)26)18-8-11-21(28-2)12-9-18/h3-13,16,23,25H,14-15H2,1-2H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD4 (1 to 477 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50028172 (CHEMBL3354010) Show SMILES COc1ccc(cc1)-c1ccc2N(CC[C@@H](Nc3ccccc3)c2c1)C(C)=O |r| Show InChI InChI=1S/C24H24N2O2/c1-17(27)26-15-14-23(25-20-6-4-3-5-7-20)22-16-19(10-13-24(22)26)18-8-11-21(28-2)12-9-18/h3-13,16,23,25H,14-15H2,1-2H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD3 (1 to 475 aa) (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
					More data for this Ligand-Target Pair