Found 4 hits for monomerid = 50028269 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50028269
(CHEMBL3342248)Show SMILES CC(=O)OC[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)S(=O)(=O)NCCCOS(N)(=O)=O |r| Show InChI InChI=1S/C17H28N2O14S2/c1-9(20)28-8-13-14(30-10(2)21)15(31-11(3)22)16(32-12(4)23)17(33-13)34(24,25)19-6-5-7-29-35(18,26)27/h13-17,19H,5-8H2,1-4H3,(H2,18,26,27)/t13-,14-,15+,16-,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 12 by stopped-flow CO2 hydration assay |
J Med Chem 57: 8635-45 (2014)
Article DOI: 10.1021/jm5012935
BindingDB Entry DOI: 10.7270/Q2QF8VFT |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50028269
(CHEMBL3342248)Show SMILES CC(=O)OC[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)S(=O)(=O)NCCCOS(N)(=O)=O |r| Show InChI InChI=1S/C17H28N2O14S2/c1-9(20)28-8-13-14(30-10(2)21)15(31-11(3)22)16(32-12(4)23)17(33-13)34(24,25)19-6-5-7-29-35(18,26)27/h13-17,19H,5-8H2,1-4H3,(H2,18,26,27)/t13-,14-,15+,16-,17+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 215 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 9 by stopped-flow CO2 hydration assay |
J Med Chem 57: 8635-45 (2014)
Article DOI: 10.1021/jm5012935
BindingDB Entry DOI: 10.7270/Q2QF8VFT |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50028269
(CHEMBL3342248)Show SMILES CC(=O)OC[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)S(=O)(=O)NCCCOS(N)(=O)=O |r| Show InChI InChI=1S/C17H28N2O14S2/c1-9(20)28-8-13-14(30-10(2)21)15(31-11(3)22)16(32-12(4)23)17(33-13)34(24,25)19-6-5-7-29-35(18,26)27/h13-17,19H,5-8H2,1-4H3,(H2,18,26,27)/t13-,14-,15+,16-,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 525 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assay |
J Med Chem 57: 8635-45 (2014)
Article DOI: 10.1021/jm5012935
BindingDB Entry DOI: 10.7270/Q2QF8VFT |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50028269
(CHEMBL3342248)Show SMILES CC(=O)OC[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)S(=O)(=O)NCCCOS(N)(=O)=O |r| Show InChI InChI=1S/C17H28N2O14S2/c1-9(20)28-8-13-14(30-10(2)21)15(31-11(3)22)16(32-12(4)23)17(33-13)34(24,25)19-6-5-7-29-35(18,26)27/h13-17,19H,5-8H2,1-4H3,(H2,18,26,27)/t13-,14-,15+,16-,17+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assay |
J Med Chem 57: 8635-45 (2014)
Article DOI: 10.1021/jm5012935
BindingDB Entry DOI: 10.7270/Q2QF8VFT |
More data for this
Ligand-Target Pair | |
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