BDBM50028343 6-(3-Bromo-phenylamino)-1H-pyrimidine-2,4-dione::CHEMBL291461

SMILES: Brc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1

InChI Key: InChIKey=CFLHCISOVMSSHJ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50028343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase III (Bacillus subtilis)	BDBM50028343 (6-(3-Bromo-phenylamino)-1H-pyrimidine-2,4-dione | ...) Show SMILES Brc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1 Show InChI InChI=1S/C10H8BrN3O2/c11-6-2-1-3-7(4-6)12-8-5-9(15)14-10(16)13-8/h1-5H,(H3,12,13,14,15,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition against Bacillus subtilis DNA topoisomerase III (wild type)				J Med Chem 23: 34-8 (1980) BindingDB Entry DOI: 10.7270/Q2125RPK
					More data for this Ligand-Target Pair
DNA topoisomerase III (Bacillus subtilis)	BDBM50028343 (6-(3-Bromo-phenylamino)-1H-pyrimidine-2,4-dione | ...) Show SMILES Brc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1 Show InChI InChI=1S/C10H8BrN3O2/c11-6-2-1-3-7(4-6)12-8-5-9(15)14-10(16)13-8/h1-5H,(H3,12,13,14,15,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA topoisomerase III (Bacillus subtilis)	BDBM50028343 (6-(3-Bromo-phenylamino)-1H-pyrimidine-2,4-dione | ...) Show SMILES Brc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1 Show InChI InChI=1S/C10H8BrN3O2/c11-6-2-1-3-7(4-6)12-8-5-9(15)14-10(16)13-8/h1-5H,(H3,12,13,14,15,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase IIIC (Bacillus subtilis)	BDBM50028343 (6-(3-Bromo-phenylamino)-1H-pyrimidine-2,4-dione | ...) Show SMILES Brc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1 Show InChI InChI=1S/C10H8BrN3O2/c11-6-2-1-3-7(4-6)12-8-5-9(15)14-10(16)13-8/h1-5H,(H3,12,13,14,15,16)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Bacillus subtilis DNA Polymerase III/azp-12(mutant).				J Med Chem 23: 34-8 (1980) BindingDB Entry DOI: 10.7270/Q2125RPK
					More data for this Ligand-Target Pair