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BDBM50028361 6-(Naphthalen-2-ylamino)-1H-pyrimidine-2,4-dione::6-(naphthalen-2-ylamino)pyrimidine-2,4(1H,3H)-dione::CHEMBL124937

SMILES: O=c1cc(Nc2ccc3ccccc3c2)[nH]c(=O)[nH]1

InChI Key: InChIKey=KADGSGKDRXSVOE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028361   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase III


(Bacillus subtilis)		BDBM50028361
PNG
(6-(Naphthalen-2-ylamino)-1H-pyrimidine-2,4-dione |...)
Show SMILES O=c1cc(Nc2ccc3ccccc3c2)[nH]c(=O)[nH]1
Show InChI InChI=1S/C14H11N3O2/c18-13-8-12(16-14(19)17-13)15-11-6-5-9-3-1-2-4-10(9)7-11/h1-8H,(H3,15,16,17,18,19)
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 6.80E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against Bacillus subtilis DNA topoisomerase III (wild type)

J Med Chem 23: 34-8 (1980)


BindingDB Entry DOI: 10.7270/Q2125RPK
More data for this
Ligand-Target Pair