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SMILES: Nc1nc2NCCSc2c(=O)[nH]1

InChI Key: InChIKey=SLOFLLQNTDOTIA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028424   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phenylalanine-4-hydroxylase


(Rattus norvegicus)		BDBM50028424
PNG
(2-Amino-7,8-dihydro-3H,6H-pyrimido[5,4-b][1,4]thia...)
Show SMILES Nc1nc2NCCSc2c(=O)[nH]1
Show InChI InChI=1S/C6H8N4OS/c7-6-9-4-3(5(11)10-6)12-2-1-8-4/h1-2H2,(H4,7,8,9,10,11)
PDB
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Similars
PubMed
 8.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for competitive binding inhibition against phenylalanine hydroxylase in rat liver

J Med Chem 26: 559-63 (1983)


BindingDB Entry DOI: 10.7270/Q2028QKN
More data for this
Ligand-Target Pair