Found 4 hits for monomerid = 50028565 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50028565
(CHEMBL3342504)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(-c2ccc(Br)cc2)c2c1nc(-c1ccc(Cl)cc1)n(C(=O)c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C31H19BrCl2N4O4S/c32-21-7-1-18(2-8-21)26-17-37(24-13-15-25(16-14-24)43(35,41)42)29-27(26)31(40)38(30(39)20-5-11-23(34)12-6-20)28(36-29)19-3-9-22(33)10-4-19/h1-17H,(H2,35,41,42) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Eur J Med Chem 87: 186-96 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.059
BindingDB Entry DOI: 10.7270/Q2PG1T90 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50028565
(CHEMBL3342504)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(-c2ccc(Br)cc2)c2c1nc(-c1ccc(Cl)cc1)n(C(=O)c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C31H19BrCl2N4O4S/c32-21-7-1-18(2-8-21)26-17-37(24-13-15-25(16-14-24)43(35,41)42)29-27(26)31(40)38(30(39)20-5-11-23(34)12-6-20)28(36-29)19-3-9-22(33)10-4-19/h1-17H,(H2,35,41,42) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 488 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Eur J Med Chem 87: 186-96 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.059
BindingDB Entry DOI: 10.7270/Q2PG1T90 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50028565
(CHEMBL3342504)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(-c2ccc(Br)cc2)c2c1nc(-c1ccc(Cl)cc1)n(C(=O)c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C31H19BrCl2N4O4S/c32-21-7-1-18(2-8-21)26-17-37(24-13-15-25(16-14-24)43(35,41)42)29-27(26)31(40)38(30(39)20-5-11-23(34)12-6-20)28(36-29)19-3-9-22(33)10-4-19/h1-17H,(H2,35,41,42) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Eur J Med Chem 87: 186-96 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.059
BindingDB Entry DOI: 10.7270/Q2PG1T90 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50028565
(CHEMBL3342504)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(-c2ccc(Br)cc2)c2c1nc(-c1ccc(Cl)cc1)n(C(=O)c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C31H19BrCl2N4O4S/c32-21-7-1-18(2-8-21)26-17-37(24-13-15-25(16-14-24)43(35,41)42)29-27(26)31(40)38(30(39)20-5-11-23(34)12-6-20)28(36-29)19-3-9-22(33)10-4-19/h1-17H,(H2,35,41,42) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
King Saud University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assay |
Eur J Med Chem 87: 186-96 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.059
BindingDB Entry DOI: 10.7270/Q2PG1T90 |
More data for this
Ligand-Target Pair | |
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