BDBM50028887 CHEMBL3359635
SMILES: [O-][N+](=O)c1cc(Cl)ccc1Sc1ccncc1
InChI Key: InChIKey=VGQCOWWMSJJMKU-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50028887 (CHEMBL3359635) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay | J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50028887 (CHEMBL3359635) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay | J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human)) | BDBM50028887 (CHEMBL3359635) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay | J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphodiesterase 7 (Homo sapiens (Human)) | BDBM50028887 (CHEMBL3359635) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay | J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC | |||||||||||
More data for this Ligand-Target Pair |