null

SMILES: CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3cc(=O)n(C)c(=O)n3C)c2)CC1

InChI Key: InChIKey=HOSHLJXJQNFOCY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50029323 (6-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3cc(=O)n(C)c(=O)n3C)c2)CC1 Show InChI InChI=1S/C27H35N5O3/c1-20(2)35-24-11-6-5-10-23(24)32-14-12-31(13-15-32)19-22-9-7-8-21(16-22)18-28-25-17-26(33)30(4)27(34)29(25)3/h5-11,16-17,20,28H,12-15,18-19H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.				J Med Chem 38: 4211-22 (1995) BindingDB Entry DOI: 10.7270/Q2C53MH2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029323 (6-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3cc(=O)n(C)c(=O)n3C)c2)CC1 Show InChI InChI=1S/C27H35N5O3/c1-20(2)35-24-11-6-5-10-23(24)32-14-12-31(13-15-32)19-22-9-7-8-21(16-22)18-28-25-17-26(33)30(4)27(34)29(25)3/h5-11,16-17,20,28H,12-15,18-19H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Affinity against the dopamine receptor D2 using [3H]spiperinone.				J Med Chem 38: 4211-22 (1995) BindingDB Entry DOI: 10.7270/Q2C53MH2
					More data for this Ligand-Target Pair