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SMILES: COc1ccc(cc1)C1(OC(C)=O)Sc2ccccc2-n2cccc12

InChI Key: InChIKey=JPKWROHZSHVEFV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029414   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit alpha-1D


(Rattus norvegicus)		BDBM50029414
PNG
(Acetic acid 4-(4-methoxy-phenyl)-4H-benzo[b]pyrrol...)
Show SMILES COc1ccc(cc1)C1(OC(C)=O)Sc2ccccc2-n2cccc12
Show InChI InChI=1S/C20H17NO3S/c1-14(22)24-20(15-9-11-16(23-2)12-10-15)19-8-5-13-21(19)17-6-3-4-7-18(17)25-20/h3-13H,1-2H3
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n/an/a 30n/an/an/an/an/an/a



Universita' degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50

J Med Chem 40: 125-31 (1997)


Article DOI: 10.1021/jm9605647
BindingDB Entry DOI: 10.7270/Q2JQ128M
More data for this
Ligand-Target Pair