BDBM50029448 3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propoxy]-9-oxo-9H-xanthen-4-yl}-propionic acid::CHEMBL129272
SMILES: CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1
InChI Key: InChIKey=AZXAHRBQFLYINX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50029448 (3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor | J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50029448 (3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor | J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50029448 (3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor | J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H | |||||||||||
More data for this Ligand-Target Pair |