BDBM50029494 2-Methyl-7-oxo-4,7-dihydro-thieno[3,2-b]pyridine-3,5-dicarboxylic acid 3-methyl ester::CHEMBL342150

SMILES: COC(=O)c1c(C)sc2c(O)cc(nc12)C(O)=O

InChI Key: InChIKey=SMNJDGDWHFJSQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Low affinity neurotrophin receptor p75NTR (Homo sapiens (Human))	BDBM50029494 (2-Methyl-7-oxo-4,7-dihydro-thieno[3,2-b]pyridine-3...) Show SMILES COC(=O)c1c(C)sc2c(O)cc(nc12)C(O)=O Show InChI InChI=1S/C11H9NO5S/c1-4-7(11(16)17-2)8-9(18-4)6(13)3-5(12-8)10(14)15/h3H,1-2H3,(H,12,13)(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [125I]- NGF binding to extracellular domain of p75 receptor				J Med Chem 38: 4439-45 (1995) BindingDB Entry DOI: 10.7270/Q2W37V9R
					More data for this Ligand-Target Pair