BDBM50029595 4-[2-(3,4-Dichloro-phenyl)-cyclopent-1-enyl]-benzenesulfonamide::4-[2-(3,4-dichlorophenyl)cyclopent-1-en-1-yl]benzenesulfonamide::CHEMBL111321

SMILES: NS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=XMYNRFMUTJHHIC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50029595 (4-[2-(3,4-Dichloro-phenyl)-cyclopent-1-enyl]-benze...) Show SMILES NS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(Cl)c(Cl)c1 |t:11| Show InChI InChI=1S/C17H15Cl2NO2S/c18-16-9-6-12(10-17(16)19)15-3-1-2-14(15)11-4-7-13(8-5-11)23(20,21)22/h4-10H,1-3H2,(H2,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 1.				J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50029595 (4-[2-(3,4-Dichloro-phenyl)-cyclopent-1-enyl]-benze...) Show SMILES NS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(Cl)c(Cl)c1 |t:11| Show InChI InChI=1S/C17H15Cl2NO2S/c18-16-9-6-12(10-17(16)19)15-3-1-2-14(15)11-4-7-13(8-5-11)23(20,21)22/h4-10H,1-3H2,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lille 2 Curated by ChEMBL					Assay Description Inhibition of human Prostaglandin G/H synthase 2				J Med Chem 44: 3223-30 (2001) BindingDB Entry DOI: 10.7270/Q2736S4D
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50029595 (4-[2-(3,4-Dichloro-phenyl)-cyclopent-1-enyl]-benze...) Show SMILES NS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(Cl)c(Cl)c1 |t:11| Show InChI InChI=1S/C17H15Cl2NO2S/c18-16-9-6-12(10-17(16)19)15-3-1-2-14(15)11-4-7-13(8-5-11)23(20,21)22/h4-10H,1-3H2,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2).				J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2
					More data for this Ligand-Target Pair