BDBM50029615 4-[2-(4-Chloro-phenyl)-cyclopent-1-enyl]-benzenesulfonamide::4-[2-(4-chlorophenyl)cyclopent-1-en-1-yl]benzenesulfonamide::CHEMBL111590
SMILES: NS(=O)(=O)c1ccc(cc1)C1=C(CCC1)c1ccc(Cl)cc1
InChI Key: InChIKey=SEOHAKCJVHNLFU-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50029615 (4-[2-(4-Chloro-phenyl)-cyclopent-1-enyl]-benzenesu...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 1. | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase (Homo sapiens (Human)) | BDBM50029615 (4-[2-(4-Chloro-phenyl)-cyclopent-1-enyl]-benzenesu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.02 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 2 Curated by ChEMBL | Assay Description Inhibition of human Prostaglandin G/H synthase 2 | J Med Chem 44: 3223-30 (2001) BindingDB Entry DOI: 10.7270/Q2736S4D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase (Homo sapiens (Human)) | BDBM50029615 (4-[2-(4-Chloro-phenyl)-cyclopent-1-enyl]-benzenesu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
More data for this Ligand-Target Pair |