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BDBM50029662 3-Amino-4-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-6-methyl-1H-pyridin-2-one::CHEMBL336237

SMILES: CCc1c(C)[nH]c(=O)c(N)c1Sc1cc(C)cc(C)c1

InChI Key: InChIKey=SBXYUVDYGNRQAF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029662   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50029662
PNG
(3-Amino-4-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-6-...)
Show SMILES CCc1c(C)[nH]c(=O)c(N)c1Sc1cc(C)cc(C)c1
Show InChI InChI=1S/C16H20N2OS/c1-5-13-11(4)18-16(19)14(17)15(13)20-12-7-9(2)6-10(3)8-12/h6-8H,5,17H2,1-4H3,(H,18,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 15n/an/an/an/an/an/a



URA 1387 CNRS

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase(RT)


J Med Chem 38: 4679-86 (1995)


BindingDB Entry DOI: 10.7270/Q2QF8RWD
More data for this
Ligand-Target Pair