BDBM50029672 CHEMBL341880::N-[4-(3,5-Dimethyl-phenylsulfanyl)-5-methyl-2-oxo-1,2-dihydro-pyridin-3-yl]-acetamide

SMILES: CC(=O)Nc1c(Sc2cc(C)cc(C)c2)c(C)c[nH]c1=O

InChI Key: InChIKey=FATTXJGHNGENGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029672 (CHEMBL341880 | N-[4-(3,5-Dimethyl-phenylsulfanyl)-...) Show SMILES CC(=O)Nc1c(Sc2cc(C)cc(C)c2)c(C)c[nH]c1=O Show InChI InChI=1S/C16H18N2O2S/c1-9-5-10(2)7-13(6-9)21-15-11(3)8-17-16(20)14(15)18-12(4)19/h5-8H,1-4H3,(H,17,20)(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair