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BDBM50029672 CHEMBL341880::N-[4-(3,5-Dimethyl-phenylsulfanyl)-5-methyl-2-oxo-1,2-dihydro-pyridin-3-yl]-acetamide

SMILES: CC(=O)Nc1c(Sc2cc(C)cc(C)c2)c(C)c[nH]c1=O

InChI Key: InChIKey=FATTXJGHNGENGH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029672   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50029672
PNG
(CHEMBL341880 | N-[4-(3,5-Dimethyl-phenylsulfanyl)-...)
Show SMILES CC(=O)Nc1c(Sc2cc(C)cc(C)c2)c(C)c[nH]c1=O
Show InChI InChI=1S/C16H18N2O2S/c1-9-5-10(2)7-13(6-9)21-15-11(3)8-17-16(20)14(15)18-12(4)19/h5-8H,1-4H3,(H,17,20)(H,18,19)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>4.00E+3n/an/an/an/an/an/a



URA 1387 CNRS

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase(RT)


J Med Chem 38: 4679-86 (1995)


BindingDB Entry DOI: 10.7270/Q2QF8RWD
More data for this
Ligand-Target Pair