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SMILES: COc1cc2c(C(=O)N(COc3cc(C)n(C)c(=O)c3)S2(=O)=O)c(c1)C(C)C

InChI Key: InChIKey=CDLMNXRBIKEYJH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029719   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neutrophil elastase


(Homo sapiens (Human))		BDBM50029719
PNG
(2-(1,6-Dimethyl-2-oxo-1,2-dihydro-pyridin-4-yloxym...)
Show SMILES COc1cc2c(C(=O)N(COc3cc(C)n(C)c(=O)c3)S2(=O)=O)c(c1)C(C)C
Show InChI InChI=1S/C19H22N2O6S/c1-11(2)15-7-13(26-5)8-16-18(15)19(23)21(28(16,24)25)10-27-14-6-12(3)20(4)17(22)9-14/h6-9,11H,10H2,1-5H3
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MMDB

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Similars
PubMed
 0.850n/an/an/an/an/an/an/an/a



Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL


Assay Description
Potency of inhibition of human leukocyte elastase is expressed as apparent binding constant

J Med Chem 38: 4687-92 (1995)


BindingDB Entry DOI: 10.7270/Q2KP816X
More data for this
Ligand-Target Pair