null
SMILES: CN1CCC2(CC1C(=Cc1ccc(I)cc1)C(=O)C2)c1cccc(O)c1
InChI Key: InChIKey=JVWALUCLXYLHJN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50029787 (5-(3-Hydroxy-phenyl)-8-[1-(4-iodo-phenyl)-meth-(E)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Ability to inhibit [3H]-(+)-pentazocine binding to guinea pig brain Sigma receptor type 1 | J Med Chem 38: 4776-85 (1996) BindingDB Entry DOI: 10.7270/Q2XW4HVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50029787 (5-(3-Hydroxy-phenyl)-8-[1-(4-iodo-phenyl)-meth-(E)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 26.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Ability to inhibit [3H]-DAMGO binding to rat brain Opioid receptor mu 1 | J Med Chem 38: 4776-85 (1996) BindingDB Entry DOI: 10.7270/Q2XW4HVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Rattus norvegicus (rat)) | BDBM50029787 (5-(3-Hydroxy-phenyl)-8-[1-(4-iodo-phenyl)-meth-(E)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 321 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Ability to inhibit [3H]-DADLE binding to rat brain delta receptor | J Med Chem 38: 4776-85 (1996) BindingDB Entry DOI: 10.7270/Q2XW4HVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50029787 (5-(3-Hydroxy-phenyl)-8-[1-(4-iodo-phenyl)-meth-(E)...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Ability to inhibit [3H]-U69,593 binding to guinea pig Opioid receptor kappa 1 | J Med Chem 38: 4776-85 (1996) BindingDB Entry DOI: 10.7270/Q2XW4HVW | |||||||||||
More data for this Ligand-Target Pair |