BDBM50029938 2-(1-Benzyl-piperidin-4-ylmethyl)-indan-1-one; hydrochloride::CHEMBL127513::CHEMBL545560

SMILES: O=C1C(CC2CCN(Cc3ccccc3)CC2)Cc2ccccc12

InChI Key: InChIKey=NCTLDXMBTJBAHY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Mus musculus (mouse))	BDBM50029938 (2-(1-Benzyl-piperidin-4-ylmethyl)-indan-1-one; hyd...) Show SMILES O=C1C(CC2CCN(Cc3ccccc3)CC2)Cc2ccccc12 Show InChI InChI=1S/C22H25NO/c24-22-20(15-19-8-4-5-9-21(19)22)14-17-10-12-23(13-11-17)16-18-6-2-1-3-7-18/h1-9,17,20H,10-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acetylcholinesterase activity in mouse brain homogenate				Bioorg Med Chem Lett 2: 871-876 (1992) Article DOI: 10.1016/S0960-894X(00)80547-8 BindingDB Entry DOI: 10.7270/Q21R6QDV
					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50029938 (2-(1-Benzyl-piperidin-4-ylmethyl)-indan-1-one; hyd...) Show SMILES O=C1C(CC2CCN(Cc3ccccc3)CC2)Cc2ccccc12 Show InChI InChI=1S/C22H25NO/c24-22-20(15-19-8-4-5-9-21(19)22)14-17-10-12-23(13-11-17)16-18-6-2-1-3-7-18/h1-9,17,20H,10-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Inhibition against Acetylcholinesterase (AChE)				J Med Chem 39: 380-7 (1996) Article DOI: 10.1021/jm950704x BindingDB Entry DOI: 10.7270/Q25D8T1Q
					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50029938 (2-(1-Benzyl-piperidin-4-ylmethyl)-indan-1-one; hyd...) Show SMILES O=C1C(CC2CCN(Cc3ccccc3)CC2)Cc2ccccc12 Show InChI InChI=1S/C22H25NO/c24-22-20(15-19-8-4-5-9-21(19)22)14-17-10-12-23(13-11-17)16-18-6-2-1-3-7-18/h1-9,17,20H,10-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against acetylcholinesterase				J Med Chem 38: 4821-9 (1996) BindingDB Entry DOI: 10.7270/Q2QC045T
					More data for this Ligand-Target Pair