BDBM50029987 12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-dihydro-6H,10H-dipyrano[2,3-f;2',3'-h]chromen-2-one::CHEMBL422798

SMILES: C[C@H]1Oc2c3C=CC(C)(C)Oc3c3c(cc(=O)oc3c2[C@H](O)[C@@H]1C)-c1ccccc1

InChI Key: InChIKey=BXENDTPSKAICGV-ZMOMAAQPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50029987 (12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-di...) Show SMILES C[C@H]1Oc2c3C=CC(C)(C)Oc3c3c(cc(=O)oc3c2[C@H](O)[C@@H]1C)-c1ccccc1 |c:5| Show InChI InChI=1S/C25H24O5/c1-13-14(2)28-22-16-10-11-25(3,4)30-23(16)19-17(15-8-6-5-7-9-15)12-18(26)29-24(19)20(22)21(13)27/h5-14,21,27H,1-4H3/t13-,14-,21-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R& D Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase in scintillation proximity assay				J Med Chem 36: 4131-8 (1994) BindingDB Entry DOI: 10.7270/Q269746K
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