BDBM50030251 CHEMBL3354078

SMILES: O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc34)CC2)CC1

InChI Key: InChIKey=LOOAMMHLLVGAEL-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50030251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50030251 (CHEMBL3354078) Show SMILES O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc34)CC2)CC1 Show InChI InChI=1S/C43H64N4O2/c48-42-22-20-38-16-8-10-18-40(38)46(42)30-12-28-44-32-24-36(25-33-44)14-6-4-2-1-3-5-7-15-37-26-34-45(35-27-37)29-13-31-47-41-19-11-9-17-39(41)21-23-43(47)49/h8-11,16-19,36-37H,1-7,12-15,20-35H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assay				J Med Chem 57: 9065-77 (2014) Article DOI: 10.1021/jm501173q BindingDB Entry DOI: 10.7270/Q2FT8NNB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50030251 (CHEMBL3354078) Show SMILES O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc34)CC2)CC1 Show InChI InChI=1S/C43H64N4O2/c48-42-22-20-38-16-8-10-18-40(38)46(42)30-12-28-44-32-24-36(25-33-44)14-6-4-2-1-3-5-7-15-37-26-34-45(35-27-37)29-13-31-47-41-19-11-9-17-39(41)21-23-43(47)49/h8-11,16-19,36-37H,1-7,12-15,20-35H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assay				J Med Chem 57: 9065-77 (2014) Article DOI: 10.1021/jm501173q BindingDB Entry DOI: 10.7270/Q2FT8NNB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50030251 (CHEMBL3354078) Show SMILES O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc34)CC2)CC1 Show InChI InChI=1S/C43H64N4O2/c48-42-22-20-38-16-8-10-18-40(38)46(42)30-12-28-44-32-24-36(25-33-44)14-6-4-2-1-3-5-7-15-37-26-34-45(35-27-37)29-13-31-47-41-19-11-9-17-39(41)21-23-43(47)49/h8-11,16-19,36-37H,1-7,12-15,20-35H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M5 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assay				J Med Chem 57: 9065-77 (2014) Article DOI: 10.1021/jm501173q BindingDB Entry DOI: 10.7270/Q2FT8NNB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50030251 (CHEMBL3354078) Show SMILES O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc34)CC2)CC1 Show InChI InChI=1S/C43H64N4O2/c48-42-22-20-38-16-8-10-18-40(38)46(42)30-12-28-44-32-24-36(25-33-44)14-6-4-2-1-3-5-7-15-37-26-34-45(35-27-37)29-13-31-47-41-19-11-9-17-39(41)21-23-43(47)49/h8-11,16-19,36-37H,1-7,12-15,20-35H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M3 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assay				J Med Chem 57: 9065-77 (2014) Article DOI: 10.1021/jm501173q BindingDB Entry DOI: 10.7270/Q2FT8NNB
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50030251 (CHEMBL3354078) Show SMILES O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc34)CC2)CC1 Show InChI InChI=1S/C43H64N4O2/c48-42-22-20-38-16-8-10-18-40(38)46(42)30-12-28-44-32-24-36(25-33-44)14-6-4-2-1-3-5-7-15-37-26-34-45(35-27-37)29-13-31-47-41-19-11-9-17-39(41)21-23-43(47)49/h8-11,16-19,36-37H,1-7,12-15,20-35H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M2 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assay				J Med Chem 57: 9065-77 (2014) Article DOI: 10.1021/jm501173q BindingDB Entry DOI: 10.7270/Q2FT8NNB
					More data for this Ligand-Target Pair