BDBM50030274 1-[4-azido-5'-O-(1,1-Dithiotriphosphate)-methyl-(2R,4R)-dihydro-2-furanyl]-5-methyl-1,2,3,4-tetrahydro-2,4-pyrimidinedione

SMILES: Cc1cn([C@H]2CC(N=[N+]=[N-])C(COP([S-])(=S)OP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=HRRQSMOCAJBZAY-KAVNDROISA-J

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50030274 (1-[4-azido-5'-O-(1,1-Dithiotriphosphate)-methyl-(2...) Show SMILES Cc1cn([C@H]2CC(N=[N+]=[N-])C(COP([S-])(=S)OP([O-])(=O)OP([O-])([O-])=O)O2)c(=O)[nH]c1=O Show InChI InChI=1S/C10H16N5O11P3S2/c1-5-3-15(10(17)12-9(5)16)8-2-6(13-14-11)7(24-8)4-23-29(30,31)26-28(21,22)25-27(18,19)20/h3,6-8H,2,4H2,1H3,(H,21,22)(H,30,31)(H,12,16,17)(H2,18,19,20)/p-4/t6?,7?,8-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Tested against HIV-1 reverse transcriptase (HIV-1 RT) with poly(rA)/(dT)12-18 as template and [methyl-3H]-dTTP as competing substrate				J Med Chem 37: 3850-4 (1994) BindingDB Entry DOI: 10.7270/Q2PV6M05
					More data for this Ligand-Target Pair