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SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O

InChI Key: InChIKey=FHMANNOWAJQNPH-RRPNLBNLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030348   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidylglycine alpha-amidating monooxygenase


(Rattus norvegicus)		BDBM50030348
PNG
(CHEMBL139052 | {(S)-2-[(R)-2-(5-Dimethylamino-naph...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C32H34N4O7S/c1-36(2)28-12-6-11-25-24(28)10-7-13-29(25)44(42,43)35-27(19-22-14-16-23(37)17-15-22)32(41)34-26(31(40)33-20-30(38)39)18-21-8-4-3-5-9-21/h3-17,26-27,35,37H,18-20H2,1-2H3,(H,33,40)(H,34,41)(H,38,39)/t26-,27+/m0/s1
PDB
MMDB

KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against peptidylglycine alpha-amidating monooxygenase (PAM) was determined

J Med Chem 37: 4430-7 (1995)


BindingDB Entry DOI: 10.7270/Q20R9NF9
More data for this
Ligand-Target Pair