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BDBM50030367 4-Mercapto-2-{(S)-2-[(naphthalene-2-carbonyl)-amino]-3-phenyl-propionylamino}-butyric acid::CHEMBL342872

SMILES: OC(=O)C(CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=NOMQSLQBBZOVCN-LBAQZLPGSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030367   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-glycine alpha-amidating monooxygenase


(Rattus norvegicus)		BDBM50030367
PNG
(4-Mercapto-2-{(S)-2-[(naphthalene-2-carbonyl)-amin...)
Show SMILES OC(=O)C(CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C24H24N2O4S/c27-22(19-11-10-17-8-4-5-9-18(17)15-19)26-21(14-16-6-2-1-3-7-16)23(28)25-20(12-13-31)24(29)30/h1-11,15,20-21,31H,12-14H2,(H,25,28)(H,26,27)(H,29,30)/t20?,21-/m0/s1
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 10n/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against peptidylglycine alpha-amidating monooxygenase (PAM) was determined

J Med Chem 37: 4430-7 (1995)


BindingDB Entry DOI: 10.7270/Q20R9NF9
More data for this
Ligand-Target Pair