BDBM50030553 4-(2-Hydroxy-ethoxymethyl)-10,11-dihydro-4H-5-thia-2,4,10-triaza-dibenzo[a,d]cycloheptene-1,3-dione::CHEMBL69934

SMILES: OCCOCn1c2Sc3ccccc3NCc2c(=O)[nH]c1=O

InChI Key: InChIKey=XTDACJNTXWRVFO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50030553 (4-(2-Hydroxy-ethoxymethyl)-10,11-dihydro-4H-5-thia...) Show SMILES OCCOCn1c2Sc3ccccc3NCc2c(=O)[nH]c1=O Show InChI InChI=1S/C14H15N3O4S/c18-5-6-21-8-17-13-9(12(19)16-14(17)20)7-15-10-3-1-2-4-11(10)22-13/h1-4,15,18H,5-8H2,(H,16,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Reverse transcriptase				J Med Chem 38: 2145-51 (1995) BindingDB Entry DOI: 10.7270/Q27943PM
					More data for this Ligand-Target Pair