BDBM50030562 CHEMBL3354130

SMILES: NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2Cl)cn1

InChI Key: InChIKey=FTPGKSNIJAXUPQ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50030562 (CHEMBL3354130) Show SMILES NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2Cl)cn1 Show InChI InChI=1S/C12H11ClN4O5S2/c13-9-3-1-2-4-10(9)24(21,22)17-12(18)16-8-5-6-11(15-7-8)23(14,19)20/h1-7H,(H2,14,19,20)(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50030562 (CHEMBL3354130) Show SMILES NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2Cl)cn1 Show InChI InChI=1S/C12H11ClN4O5S2/c13-9-3-1-2-4-10(9)24(21,22)17-12(18)16-8-5-6-11(15-7-8)23(14,19)20/h1-7H,(H2,14,19,20)(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50030562 (CHEMBL3354130) Show SMILES NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2Cl)cn1 Show InChI InChI=1S/C12H11ClN4O5S2/c13-9-3-1-2-4-10(9)24(21,22)17-12(18)16-8-5-6-11(15-7-8)23(14,19)20/h1-7H,(H2,14,19,20)(H2,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50030562 (CHEMBL3354130) Show SMILES NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccccc2Cl)cn1 Show InChI InChI=1S/C12H11ClN4O5S2/c13-9-3-1-2-4-10(9)24(21,22)17-12(18)16-8-5-6-11(15-7-8)23(14,19)20/h1-7H,(H2,14,19,20)(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair