BDBM50030976 5-(3-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL125973

SMILES: OCCOCn1cc(Cc2cccc(F)c2)c(=O)[nH]c1=O

InChI Key: InChIKey=ZHMNGVLIPCBMMT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine phosphorylase 1 (Mus musculus)	BDBM50030976 (5-(3-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...) Show SMILES OCCOCn1cc(Cc2cccc(F)c2)c(=O)[nH]c1=O Show InChI InChI=1S/C14H15FN2O4/c15-12-3-1-2-10(7-12)6-11-8-17(9-21-5-4-18)14(20)16-13(11)19/h1-3,7-8,18H,4-6,9H2,(H,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair