BDBM50031010 1-(2-Hydroxy-ethoxymethyl)-5-(3-methoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL123683

SMILES: COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1

InChI Key: InChIKey=NATVNSLPKFUVIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine phosphorylase 1 (Mus musculus)	BDBM50031010 (1-(2-Hydroxy-ethoxymethyl)-5-(3-methoxy-benzyl)-1H...) Show SMILES COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C15H18N2O5/c1-21-13-4-2-3-11(8-13)7-12-9-17(10-22-6-5-18)15(20)16-14(12)19/h2-4,8-9,18H,5-7,10H2,1H3,(H,16,19,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description The compound was tested for inhibition of uridine phosphorylase (UrdPase) from murine liver Value refers to activity for apparent Ki value				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair