BDBM50031254 CHEMBL275433::[5-(7-Amino-5-chloro-imidazo[4,5-b]pyridin-3-yl)-tetrahydro-furan-2-yl]-methanol

SMILES: Nc1cc(Cl)nc2n(cnc12)C1CCC(CO)O1

InChI Key: InChIKey=YVHAWFAZBNGIEP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50031254 (CHEMBL275433 | [5-(7-Amino-5-chloro-imidazo[4,5-b]...) Show SMILES Nc1cc(Cl)nc2n(cnc12)C1CCC(CO)O1 Show InChI InChI=1S/C11H13ClN4O2/c12-8-3-7(13)10-11(15-8)16(5-14-10)9-2-1-6(4-17)18-9/h3,5-6,9,17H,1-2,4H2,(H2,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.55E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligand				J Med Chem 38: 1174-88 (1995) BindingDB Entry DOI: 10.7270/Q2HQ40KN
					More data for this Ligand-Target Pair
Adenosine deaminase (Bos taurus (bovine))	BDBM50031254 (CHEMBL275433 | [5-(7-Amino-5-chloro-imidazo[4,5-b]...) Show SMILES Nc1cc(Cl)nc2n(cnc12)C1CCC(CO)O1 Show InChI InChI=1S/C11H13ClN4O2/c12-8-3-7(13)10-11(15-8)16(5-14-10)9-2-1-6(4-17)18-9/h3,5-6,9,17H,1-2,4H2,(H2,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Inhibition calf intestine adenosine deaminase				J Med Chem 38: 4019-25 (1995) BindingDB Entry DOI: 10.7270/Q2RB757R
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50031254 (CHEMBL275433 | [5-(7-Amino-5-chloro-imidazo[4,5-b]...) Show SMILES Nc1cc(Cl)nc2n(cnc12)C1CCC(CO)O1 Show InChI InChI=1S/C11H13ClN4O2/c12-8-3-7(13)10-11(15-8)16(5-14-10)9-2-1-6(4-17)18-9/h3,5-6,9,17H,1-2,4H2,(H2,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.				J Med Chem 38: 1174-88 (1995) BindingDB Entry DOI: 10.7270/Q2HQ40KN
					More data for this Ligand-Target Pair