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BDBM50031324 5',7'-dichlorospiro[4,5-dihydro-1H-imidazole-4,2'-(1',2',3',4'-tetrahydronaphthalene)]::CHEMBL338683

SMILES: Clc1cc(Cl)c2CCC3(CNC=N3)Cc2c1

InChI Key: InChIKey=JVXCQBZATLABHQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031324   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50031324
PNG
(5',7'-dichlorospiro[4,5-dihydro-1H-imidazole-4,2'-...)
Show SMILES Clc1cc(Cl)c2CCC3(CNC=N3)Cc2c1 |c:11|
Show InChI InChI=1S/C12H12Cl2N2/c13-9-3-8-5-12(6-15-7-16-12)2-1-10(8)11(14)4-9/h3-4,7H,1-2,5-6H2,(H,15,16)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
3n/an/an/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Binding affinity towards Alpha-2A adrenergic receptor in human platelets using [3H]-RX-821002 as radioligand


J Med Chem 38: 4056-69 (1995)


BindingDB Entry DOI: 10.7270/Q2DV1HXN
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(NEONATAL RAT)
BDBM50031324
PNG
(5',7'-dichlorospiro[4,5-dihydro-1H-imidazole-4,2'-...)
Show SMILES Clc1cc(Cl)c2CCC3(CNC=N3)Cc2c1 |c:11|
Show InChI InChI=1S/C12H12Cl2N2/c13-9-3-8-5-12(6-15-7-16-12)2-1-10(8)11(14)4-9/h3-4,7H,1-2,5-6H2,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
95n/an/an/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Binding affinity towards Alpha-2B adrenergic receptor in neonatal rat lung using [3H]-RX-821002 as radioligand


J Med Chem 38: 4056-69 (1995)


BindingDB Entry DOI: 10.7270/Q2DV1HXN
More data for this
Ligand-Target Pair