BDBM50031779 (R)-2-(4-Butyrylamino-butyl)-N*4*-hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::(R)-2-(4-butyramidobutyl)-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)succinamide::CHEMBL313356

SMILES: CCCC(=O)NCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC

InChI Key: InChIKey=FPIZTGFSDBBQIE-MSOLQXFVSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50031779 ((R)-2-(4-Butyrylamino-butyl)-N*4*-hydroxy-N*1*-((S...) Show SMILES CCCC(=O)NCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC Show InChI InChI=1S/C22H34N4O5/c1-3-9-19(27)24-13-8-7-12-17(15-20(28)26-31)21(29)25-18(22(30)23-2)14-16-10-5-4-6-11-16/h4-6,10-11,17-18,31H,3,7-9,12-15H2,1-2H3,(H,23,30)(H,24,27)(H,25,29)(H,26,28)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibition of human neutrophil collagenase(HNC), MMP-8				J Med Chem 38: 2570-81 (1995) BindingDB Entry DOI: 10.7270/Q2GM86B5
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50031779 ((R)-2-(4-Butyrylamino-butyl)-N*4*-hydroxy-N*1*-((S...) Show SMILES CCCC(=O)NCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC Show InChI InChI=1S/C22H34N4O5/c1-3-9-19(27)24-13-8-7-12-17(15-20(28)26-31)21(29)25-18(22(30)23-2)14-16-10-5-4-6-11-16/h4-6,10-11,17-18,31H,3,7-9,12-15H2,1-2H3,(H,23,30)(H,24,27)(H,25,29)(H,26,28)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibitory potency against human stromelysin, MMP-3				J Med Chem 38: 2570-81 (1995) BindingDB Entry DOI: 10.7270/Q2GM86B5
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50031779 ((R)-2-(4-Butyrylamino-butyl)-N*4*-hydroxy-N*1*-((S...) Show SMILES CCCC(=O)NCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC Show InChI InChI=1S/C22H34N4O5/c1-3-9-19(27)24-13-8-7-12-17(15-20(28)26-31)21(29)25-18(22(30)23-2)14-16-10-5-4-6-11-16/h4-6,10-11,17-18,31H,3,7-9,12-15H2,1-2H3,(H,23,30)(H,24,27)(H,25,29)(H,26,28)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	708	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50031779 ((R)-2-(4-Butyrylamino-butyl)-N*4*-hydroxy-N*1*-((S...) Show SMILES CCCC(=O)NCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC Show InChI InChI=1S/C22H34N4O5/c1-3-9-19(27)24-13-8-7-12-17(15-20(28)26-31)21(29)25-18(22(30)23-2)14-16-10-5-4-6-11-16/h4-6,10-11,17-18,31H,3,7-9,12-15H2,1-2H3,(H,23,30)(H,24,27)(H,25,29)(H,26,28)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sterling Winthrop Pharmaceuticals Research Division Curated by ChEMBL					Assay Description Inhibitory potency against human fibroblast collagenase, MMP-1				J Med Chem 38: 2570-81 (1995) BindingDB Entry DOI: 10.7270/Q2GM86B5
					More data for this Ligand-Target Pair