Found 3 hits for monomerid = 50031822 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human)) | BDBM50031822
(CHEMBL3360895)Show SMILES CCOc1nc(N)nc2[nH]c(SCC(=O)Nc3ccc(OC)c(OC)c3)nc12 Show InChI InChI=1S/C17H20N6O4S/c1-4-27-15-13-14(21-16(18)23-15)22-17(20-13)28-8-12(24)19-9-5-6-10(25-2)11(7-9)26-3/h5-7H,4,8H2,1-3H3,(H,19,24)(H3,18,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description
Competitive inhibition of human NPP1 using p-Nph-5'-TMP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 57: 10080-100 (2014)
Article DOI: 10.1021/jm501434y
BindingDB Entry DOI: 10.7270/Q2377B9S |
More data for this
Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human)) | BDBM50031822
(CHEMBL3360895)Show SMILES CCOc1nc(N)nc2[nH]c(SCC(=O)Nc3ccc(OC)c(OC)c3)nc12 Show InChI InChI=1S/C17H20N6O4S/c1-4-27-15-13-14(21-16(18)23-15)22-17(20-13)28-8-12(24)19-9-5-6-10(25-2)11(7-9)26-3/h5-7H,4,8H2,1-3H3,(H,19,24)(H3,18,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description
Inhibition of human NPP1 using p-Nph-5'-TMP as substrate |
J Med Chem 57: 10080-100 (2014)
Article DOI: 10.1021/jm501434y
BindingDB Entry DOI: 10.7270/Q2377B9S |
More data for this
Ligand-Target Pair | |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human)) | BDBM50031822
(CHEMBL3360895)Show SMILES CCOc1nc(N)nc2[nH]c(SCC(=O)Nc3ccc(OC)c(OC)c3)nc12 Show InChI InChI=1S/C17H20N6O4S/c1-4-27-15-13-14(21-16(18)23-15)22-17(20-13)28-8-12(24)19-9-5-6-10(25-2)11(7-9)26-3/h5-7H,4,8H2,1-3H3,(H,19,24)(H3,18,20,21,22,23) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description
Competitive inhibition of human NPP1 using ATP as substrate by Lineweaver-Burk plot analysis |
J Med Chem 57: 10080-100 (2014)
Article DOI: 10.1021/jm501434y
BindingDB Entry DOI: 10.7270/Q2377B9S |
More data for this
Ligand-Target Pair | |
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