BindingDB PrimarySearch

null

SMILES: CCN1C(=O)N\C(=C\c2ccc(OCc3ccc(cc3)C(O)=O)c(I)c2)C1=O

InChI Key: InChIKey=KQGWVYRXAQEKEX-MHWRWJLKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50031910
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 5 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of STEP (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 9 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MEG2 (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase Slingshot homolog 2 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of SSH2 (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase 1A (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of PPM1A (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein phosphatase 1G (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of PPM1G (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 18 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of PTPN18 (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Homo sapiens (Human))	BDBM50031910 (CHEMBL3360908) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of VHR (unknown origin) assessed as reduction in pNPP hydrolysis				J Med Chem 57: 9309-22 (2014) Article DOI: 10.1021/jm500692u BindingDB Entry DOI: 10.7270/Q2ZG6TVJ
Shandong University Curated by ChEMBL					More data for this Ligand-Target Pair