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BDBM50031959 2-Butyl-5-chloro-3-[5-oxo-11-(1H-tetrazol-5-yl)-5H-dibenzo[a,d]cyclohepten-3-ylmethyl]-3H-imidazole-4-carboxylic acid::CHEMBL327535

SMILES: CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1

InChI Key: InChIKey=CWRWYPBWBJZCSR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031959   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50031959
PNG
(2-Butyl-5-chloro-3-[5-oxo-11-(1H-tetrazol-5-yl)-5H...)
Show SMILES CCCCc1nc(Cl)c(C(O)=O)n1Cc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1
Show InChI InChI=1S/C25H21ClN6O3/c1-2-3-8-20-27-23(26)21(25(34)35)32(20)13-14-9-10-17-18(11-14)22(33)16-7-5-4-6-15(16)12-19(17)24-28-30-31-29-24/h4-7,9-12H,2-3,8,13H2,1H3,(H,34,35)(H,28,29,30,31)
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PC cid
PC sid
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PubMed
2.10n/an/an/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1


J Med Chem 38: 2728-41 (1995)


BindingDB Entry DOI: 10.7270/Q23B5Z5Q
More data for this
Ligand-Target Pair