BDBM50031989 1-[8-Hydroxymethyl-4-(4-hydroxy-2-methyl-phenylamino)-quinolin-3-yl]-2-methyl-propan-1-one::CHEMBL96549
SMILES: CC(C)C(=O)c1cnc2c(CO)cccc2c1Nc1ccc(O)cc1C
InChI Key: InChIKey=NJPKTOOYCKVHLI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50031989 (1-[8-Hydroxymethyl-4-(4-hydroxy-2-methyl-phenylami...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | 7.0 | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of K+ -stimulated gastric ATPase activity was measured using lyophilized gastric vesicles at pH 7 | J Med Chem 38: 2748-62 (1995) BindingDB Entry DOI: 10.7270/Q2ZK5FPD | |||||||||||
More data for this Ligand-Target Pair |