BDBM50032112 CHEMBL421746::N*2*-(4-Fluoro-2-methyl-phenyl)-N*4*-methyl-N*4*-phenyl-thieno[3,2-d]pyrimidine-2,4-diamine

SMILES: CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2ccsc12

InChI Key: InChIKey=FTZCQVACADOUBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50032112 (CHEMBL421746 | N*2*-(4-Fluoro-2-methyl-phenyl)-N*4...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2ccsc12 Show InChI InChI=1S/C20H17FN4S/c1-13-12-14(21)8-9-16(13)22-20-23-17-10-11-26-18(17)19(24-20)25(2)15-6-4-3-5-7-15/h3-12H,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair