BDBM50032222 6-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-nicotinic acid::CHEMBL92926

SMILES: C\C(=C/c1ccc(cn1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C

InChI Key: InChIKey=GAZWXMUOJOGOHH-RVDMUPIBSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50032222 (6-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1ccc(cn1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15(11-18-8-7-17(14-25-18)22(26)27)19-13-21-20(12-16(19)2)23(3,4)9-10-24(21,5)6/h7-8,11-14H,9-10H2,1-6H3,(H,26,27)/b15-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR alpha				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Homo sapiens (Human))	BDBM50032222 (6-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1ccc(cn1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15(11-18-8-7-17(14-25-18)22(26)27)19-13-21-20(12-16(19)2)23(3,4)9-10-24(21,5)6/h7-8,11-14H,9-10H2,1-6H3,(H,26,27)/b15-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	374	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR gamma				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50032222 (6-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1ccc(cn1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15(11-18-8-7-17(14-25-18)22(26)27)19-13-21-20(12-16(19)2)23(3,4)9-10-24(21,5)6/h7-8,11-14H,9-10H2,1-6H3,(H,26,27)/b15-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032222 (6-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1ccc(cn1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15(11-18-8-7-17(14-25-18)22(26)27)19-13-21-20(12-16(19)2)23(3,4)9-10-24(21,5)6/h7-8,11-14H,9-10H2,1-6H3,(H,26,27)/b15-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoid X receptor RXR alpha				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair