BDBM50032235 6-(3,5-Dimethyl-benzyl)-1-ethoxymethyl-5-ethyl-1H-pyrimidine-2,4-dione::6-(3,5-dimethylbenzyl)-1-ethoxymethyl-5-ethyl-1,2,3,4-tetrahydro-2,4-pyrimidine dione::CHEMBL310976

SMILES: CCOCn1c(Cc2cc(C)cc(C)c2)c(CC)c(=O)[nH]c1=O

InChI Key: InChIKey=LNEPZLRCYLNOIU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50032235 (6-(3,5-Dimethyl-benzyl)-1-ethoxymethyl-5-ethyl-1H-...) Show SMILES CCOCn1c(Cc2cc(C)cc(C)c2)c(CC)c(=O)[nH]c1=O Show InChI InChI=1S/C18H24N2O3/c1-5-15-16(10-14-8-12(3)7-13(4)9-14)20(11-23-6-2)18(22)19-17(15)21/h7-9H,5-6,10-11H2,1-4H3,(H,19,21,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase				J Med Chem 40: 4257-64 (1998) Article DOI: 10.1021/jm970110p BindingDB Entry DOI: 10.7270/Q2WS8SC3
					More data for this Ligand-Target Pair