BDBM50032236 6-(3,5-Dimethyl-benzyl)-1-(2-hydroxy-ethoxymethyl)-5-isopropyl-1H-pyrimidine-2,4-dione::CHEMBL97347

SMILES: CC(C)c1c(Cc2cc(C)cc(C)c2)n(COCCO)c(=O)[nH]c1=O

InChI Key: InChIKey=DZZBAINGKYKBHW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50032236 (6-(3,5-Dimethyl-benzyl)-1-(2-hydroxy-ethoxymethyl)...) Show SMILES CC(C)c1c(Cc2cc(C)cc(C)c2)n(COCCO)c(=O)[nH]c1=O Show InChI InChI=1S/C19H26N2O4/c1-12(2)17-16(10-15-8-13(3)7-14(4)9-15)21(11-25-6-5-22)19(24)20-18(17)23/h7-9,12,22H,5-6,10-11H2,1-4H3,(H,20,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase				J Med Chem 40: 4257-64 (1998) Article DOI: 10.1021/jm970110p BindingDB Entry DOI: 10.7270/Q2WS8SC3
					More data for this Ligand-Target Pair