BDBM50032401 3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL101300
SMILES: CC1C2Cc3ccc(F)cc3C1(C)CCN2Cc1ccccc1
InChI Key: InChIKey=GMSWWAYLXZJZCL-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50032401 (3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand. | J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50032401 (3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand. | J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50032401 (3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement. | J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50032401 (3-Benzyl-8-fluoro-6,11-dimethyl-1,2,3,4,5,6-hexahy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 264 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity at Sigma receptor type 2 on rat liver membranes receptor by [3H]DTG displacement. | J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP | |||||||||||
More data for this Ligand-Target Pair |