null

SMILES: CCn1c(NC2CCCC2)nc2c(csc2c1=O)N1CCN(CC1=O)C(=O)OC(C)(C)C

InChI Key: InChIKey=MRXRVJQSSLSKLK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50032550 (CHEMBL3354182) Show SMILES CCn1c(NC2CCCC2)nc2c(csc2c1=O)N1CCN(CC1=O)C(=O)OC(C)(C)C Show InChI InChI=1S/C22H31N5O4S/c1-5-26-19(29)18-17(24-20(26)23-14-8-6-7-9-14)15(13-32-18)27-11-10-25(12-16(27)28)21(30)31-22(2,3)4/h13-14H,5-12H2,1-4H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				J Med Chem 57: 9844-54 (2014) Article DOI: 10.1021/jm5008215 BindingDB Entry DOI: 10.7270/Q228096D
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50032550 (CHEMBL3354182) Show SMILES CCn1c(NC2CCCC2)nc2c(csc2c1=O)N1CCN(CC1=O)C(=O)OC(C)(C)C Show InChI InChI=1S/C22H31N5O4S/c1-5-26-19(29)18-17(24-20(26)23-14-8-6-7-9-14)15(13-32-18)27-11-10-25(12-16(27)28)21(30)31-22(2,3)4/h13-14H,5-12H2,1-4H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				J Med Chem 57: 9844-54 (2014) Article DOI: 10.1021/jm5008215 BindingDB Entry DOI: 10.7270/Q228096D
					More data for this Ligand-Target Pair