BDBM50032555 4-[2-Methyl-1-(2-morpholin-4-yl-ethyl)-1H-indole-3-carbonyl]-naphthalene-1-carbonitrile::CHEMBL81683
SMILES: Cc1c(C(=O)c2ccc(C#N)c3ccccc23)c2ccccc2n1CCN1CCOCC1
InChI Key: InChIKey=UPMARMNIDOFZNU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor (Rattus norvegicus (rat)) | BDBM50032555 (4-[2-Methyl-1-(2-morpholin-4-yl-ethyl)-1H-indole-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.51E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Research Division Curated by ChEMBL | Assay Description Cannabinoid receptor 1 binding affinity by measuring its ability to displace [3H]WIN-55212-2 in rat forebrain membranes | J Med Chem 41: 4521-32 (1998) Article DOI: 10.1021/jm980305c BindingDB Entry DOI: 10.7270/Q2XD14F0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor (Rattus norvegicus (rat)) | BDBM50032555 (4-[2-Methyl-1-(2-morpholin-4-yl-ethyl)-1H-indole-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.51E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Bioorganic & Petroleum Chemistry Curated by ChEMBL | Assay Description Binding affinity at cannabinoid receptor 1 using rat brain membranes | J Med Chem 44: 2411-20 (2001) Article DOI: 10.1021/jm010858e BindingDB Entry DOI: 10.7270/Q2GT5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM50032555 (4-[2-Methyl-1-(2-morpholin-4-yl-ethyl)-1H-indole-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Research Division Curated by ChEMBL | Assay Description Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes. | J Med Chem 38: 3094-105 (1995) BindingDB Entry DOI: 10.7270/Q2DN442Z | |||||||||||
More data for this Ligand-Target Pair |