BDBM50032607 CHEMBL3354175

SMILES: CCn1c(NC2CCCC2)nc2c(csc2c1=O)-c1ccccc1

InChI Key: InChIKey=AIOOOOYCTWPHCO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50032607 (CHEMBL3354175) Show SMILES CCn1c(NC2CCCC2)nc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C19H21N3OS/c1-2-22-18(23)17-16(21-19(22)20-14-10-6-7-11-14)15(12-24-17)13-8-4-3-5-9-13/h3-5,8-9,12,14H,2,6-7,10-11H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of human PDE4B1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				J Med Chem 57: 9844-54 (2014) Article DOI: 10.1021/jm5008215 BindingDB Entry DOI: 10.7270/Q228096D
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50032607 (CHEMBL3354175) Show SMILES CCn1c(NC2CCCC2)nc2c(csc2c1=O)-c1ccccc1 Show InChI InChI=1S/C19H21N3OS/c1-2-22-18(23)17-16(21-19(22)20-14-10-6-7-11-14)15(12-24-17)13-8-4-3-5-9-13/h3-5,8-9,12,14H,2,6-7,10-11H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				J Med Chem 57: 9844-54 (2014) Article DOI: 10.1021/jm5008215 BindingDB Entry DOI: 10.7270/Q228096D
					More data for this Ligand-Target Pair