null

SMILES: CC(C)N1CCN(CC1)c1ccc(cc1)-c1cc2nc(NCC=C)n(C)c(=O)c2s1

InChI Key: InChIKey=GUFLGQQHIPWGPE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50032609 (CHEMBL3354155) Show SMILES CC(C)N1CCN(CC1)c1ccc(cc1)-c1cc2nc(NCC=C)n(C)c(=O)c2s1 Show InChI InChI=1S/C23H29N5OS/c1-5-10-24-23-25-19-15-20(30-21(19)22(29)26(23)4)17-6-8-18(9-7-17)28-13-11-27(12-14-28)16(2)3/h5-9,15-16H,1,10-14H2,2-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of PDE7A (unknown origin)				Bioorg Med Chem Lett 25: 649-53 (2015) Article DOI: 10.1016/j.bmcl.2014.11.090 BindingDB Entry DOI: 10.7270/Q2542Q6P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50032609 (CHEMBL3354155) Show SMILES CC(C)N1CCN(CC1)c1ccc(cc1)-c1cc2nc(NCC=C)n(C)c(=O)c2s1 Show InChI InChI=1S/C23H29N5OS/c1-5-10-24-23-25-19-15-20(30-21(19)22(29)26(23)4)17-6-8-18(9-7-17)28-13-11-27(12-14-28)16(2)3/h5-9,15-16H,1,10-14H2,2-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 607-8042 Curated by ChEMBL					Assay Description Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation counting				J Med Chem 57: 9844-54 (2014) Article DOI: 10.1021/jm5008215 BindingDB Entry DOI: 10.7270/Q228096D
					More data for this Ligand-Target Pair