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SMILES: Clc1cc(Br)c2OC(CCc3cccnc3)CC(=O)c2c1

InChI Key: InChIKey=YDXRWQYUVIAKSB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032635   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NAD-dependent protein deacetylase sirtuin-2


(Homo sapiens (Human))		BDBM50032635
PNG
(CHEMBL3354201)
Show SMILES Clc1cc(Br)c2OC(CCc3cccnc3)CC(=O)c2c1
Show InChI InChI=1S/C16H13BrClNO2/c17-14-7-11(18)6-13-15(20)8-12(21-16(13)14)4-3-10-2-1-5-19-9-10/h1-2,5-7,9,12H,3-4,8H2
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



University of Gothenburg

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged sirtuin-2 (unknown origin) using KI179 as substrate after 1 hr by fluorescence assay

J Med Chem 57: 9870-88 (2014)


Article DOI: 10.1021/jm500930h
BindingDB Entry DOI: 10.7270/Q2ST7RG2
More data for this
Ligand-Target Pair