BDBM50032668 4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-benzoic acid::CHEMBL25244

SMILES: [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6]

InChI Key: InChIKey=QDSXVZMDVWIEJZ-UHFFFAOYSA-N

Data: 3 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50032668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid X receptor gamma (Mus musculus)	BDBM50032668 (4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C26H32O2/c1-16(2)23(18-8-10-19(11-9-18)24(27)28)20-15-22-21(14-17(20)3)25(4,5)12-13-26(22,6)7/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-gamma was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032668 (4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C26H32O2/c1-16(2)23(18-8-10-19(11-9-18)24(27)28)20-15-22-21(14-17(20)3)25(4,5)12-13-26(22,6)7/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to bind directly to Retinoic acid receptor RXR-alpha was evaluated in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Mus musculus)	BDBM50032668 (4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C26H32O2/c1-16(2)23(18-8-10-19(11-9-18)24(27)28)20-15-22-21(14-17(20)3)25(4,5)12-13-26(22,6)7/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-gamma was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50032668 (4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C26H32O2/c1-16(2)23(18-8-10-19(11-9-18)24(27)28)20-15-22-21(14-17(20)3)25(4,5)12-13-26(22,6)7/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity to Retinoic acid receptor RXR-beta was determined in a competitive binding assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032668 (4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C26H32O2/c1-16(2)23(18-8-10-19(11-9-18)24(27)28)20-15-22-21(14-17(20)3)25(4,5)12-13-26(22,6)7/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-alpha was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Mus musculus)	BDBM50032668 (4-[2-Methyl-1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...) Show SMILES [#6]\[#6](-[#6])=[#6](/c1ccc(cc1)-[#6](-[#8])=O)-c1cc2c(cc1-[#6])C([#6])([#6])[#6]-[#6]C2([#6])[#6] Show InChI InChI=1S/C26H32O2/c1-16(2)23(18-8-10-19(11-9-18)24(27)28)20-15-22-21(14-17(20)3)25(4,5)12-13-26(22,6)7/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Ability to activate gene expression at Retinoic acid receptor RXR-beta was evaluated in a cotransfection assay.				J Med Chem 38: 3146-55 (1995) BindingDB Entry DOI: 10.7270/Q2542MMT
					More data for this Ligand-Target Pair